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CT引导射频消融术治疗肺癌35例
张开贤 李苓 邢超 张开国 袁倩倩 郝崇礼 满其荣 王伟 杨森
山东滕州市中心人民医院肿瘤科 ,山东 滕州 277500
【摘要】 目的:探讨CT引导下射频消融术(RFA)治疗肺癌的疗效及安全性。方法:35例肺癌进行了CT引导下射频消融治疗,其中鳞癌12例,腺癌20例,鳞腺癌1例,大细胞癌2例。中央型肺癌4例,周围型肺癌31例。肿瘤直径≤3cm 6例,3~5cm 21例,5cm 8例。结果:射频消融过程中多数病灶阴影增大,边缘模糊,部分病灶出现蜂窝气泡样改变,术后3个月复查CT显示28个病灶缩小,其中CR1例,PR例27例,SD4例,PD3例,总有效率(CR+PR)为80.0%。术后少量咯血5例,气胸5例,轻度发热7例。结论:CT引导RFA治疗肺癌是安全有效的微创技术,值得推广应用。
【关键词】 肺肿瘤;射频消融术;放射学,介入性
CT-guided radiofrequency ablation in treating 35 cases of cancer Zhang Kai-xian, Li Ling, Xing Chao, Zhang Kai-guo,Yuan Qian-qian, Hao Chong-li, Man Qi-rong, Wang Wei, Yang Sen, Teng ying.
Depatment of cancer center, Tengzhou Peoples Hospital, Tengzhou 277500, China【Abstract】Objective: To access the security and therapeutic value of CT-guided radiofrequency ablation (RFA) treatment in non-small cell lung cancer(NSCLC). Methods: 35 patients with NSCLC were treated with CT guided RFA, which including 4 cases of central lung cancer and 31 cases of peripheral lung cancer, as well as in different pathology type and tumour size. Result: During the process of RFA, the volume of lesions in majority cases become lager , also with a fuzzy edge. Some lesions show bubble-like changes. After three months later, CT showed that 28 lesions reduced, including CR 1 cases, PR 27 cases, SD 4 cases and PD 3 cases.The total effective rate (CR + PR) was 80.0%. Little amount of hemoptysis in 5 cases, pneumothorax in 5 cases, 7 cases of mild
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【通讯作者简介】 张开贤,男,山东滕州人,主任医师,主要从事肿瘤放化疗和介入治疗工作。Tel:86-0632-5535781 E-mail:kaixianzhang@Y
fever. Conclusion: CT guided RFA is a safe, effective and minimal invasive therapeutic method for lung cancer.
【KEYWORDS】lung neoplasms; radiofrequency ablation; radiology, interventional
射频消融术( radiofrequency thermal ablation,RFA)已经广泛地用于肝脏、肾脏、前列腺等实质性脏器肿瘤的治疗,并取得了理想的疗效[1-2],近来射频开始用于治疗肺癌[3-5]。2007年8月至2009年10月,我们对35例非小细胞肺癌进行了多层螺旋CT引导射频消融术,取得一定疗效,现报告如下。
与方法
1.1 资料 本组患者共35例,男性23例,女性12例,年龄50~78 岁,中位年龄65岁。术前全部经CT引导下经皮穿刺活检获取病理学诊断,其中鳞癌12例
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