Chinese Traditional Medicine-Drug.ppt

Chinese Traditional Medicine: Medicinal substances and drug formulation Xiaoda Yang, Ph.D, Professor School of Pharm. Sci./Peking Univ. Drugs (藥) and music (樂) Medicines help to bring the body back to balanced state More references Natural source of TCM Roots Rhizome Stem Bark Flower Fruit Special plant preparations One plant, three medical products Imported herbals Fungus TCM products (I)-Fresh herbal TCM products (II)- Preserved slices TCM products (III) ---Medical drinks (I) TCM products (III) --- Medical drinks (II) TCM products (III) --- Medical drinks (III) TCM products (IV)---Prepared drugs TCM formulation strategy Fundamental rules Whatever the diseases, the goal of treatment is to retrieve the balance of the body Eliminating pathogens while correcting the body functions Appropriate therapeutic steps Individual therapy Prevention all the way Primary methods Opening into Warming Promotion Excretion by sweat, vomit, diarrhea Inhibition Intoxication Medicinal Properties of herbals Drug classification by Eight diagram 桂枝Ramuli Cinnamoi: the heater of the body 人参Gingseng: the master herb 百合lily：a medical food for lung 当归Angelica sinensis：a key for beauty 柴胡Bupleurum chinense: the “ice” for pathological heat 穿心莲A. paniculata, a herbal for women 冬凌草R. Rubescens, a magic tea from Taihang mountain “三七” notoginseng: special for men Traditional use: Analgesic Internal external wounds Heart protection Reduce blood pressure Recent discovery--- Effective in prostate treatment Prevention of co Formulation strategy 君 King (chief) herb Treat the principal problems 臣 Minister (deputy) herb Treat the other major problems 佐 Assistant herb Treat accompanying symptoms; Moderate the harshness or toxicity of the primary substances; 使 Messenger herb Help with the dosage or the taste Example: Ramuli Cinnamomi Decoction The formulation 桂枝Ramulus Cinnamomi （9g） Spice-fragrant, sweet, warm, outward, non-toxic 芍药Radix Paeoniae （9g） Bitter, sour, slightly cool, inward