1前沿技术动态(高通量测序内部培训资料).pdf

基因组学、生物信息学前沿技术动态 BGI-Shenzhen Outline  Introduction  Sequencing technologies  Bioinformatic analysis  Applications  Tree of Life (de novo)  Population evolution and Breeding (Resequencing)  Disease (Resequencing)  Epigenomics  Transcriptomics  Metagenomics  Proteomics Growth of NCBI Growth of NCBI 60,000 50,000 ） b G 40,000 （ 基 30,000 碱 亿 20,000 十 10,000 0 2 4 6 8 0 2 4 6 8 0 2 4 6 8 0 8 8 8 8 9 9 9 9 9 0 0 0 0 0 1 9 9 9 9 9 9 9 9 9 0 0 0 0 0 0 1 1 1 1 1 1 1 1 1 2 2 2 2 2 2 年份 BGI is constructing supercomputing platform to match the requirements Solution for wet labs： Cloud computing Cloud computing From genotype to Phenotype! mRNA Protein Genome Genotype Epigenetics Metabolome Phenotype ncRNA Genotype Intermediate Phenotype Molecular Phenotype Outline  Introduction  Sequencing technologies  Bioinformatics analysis  Applications  Tree of Life (de novo)  Population evolution and Breeding (Resequencing)  Disease (Resequencing)  Epigenomics  Transcriptomics  Metagenomics  Proteomics The fast-revolution of DNA sequencing technology List of available tehnologies: • 3730, AB (Sanger me