the effect of the acetone extract of arctotis arctotoides (asteraceae) on the growth and ultrastructure of some opportunistic fungi associated with hivaids丙酮提取物的效果arctotis arctotoides(菊科)一些机会性真菌的生长和超微结构与条件有关.pdf

Int. J. Mol. Sci. 2011, 12, 9226-9235; doi:10.3390/ijm OPEN ACCESS International Journal of Molecular Sciences ISSN 1422-0067 /journal/ijms Article The Effect of the Acetone Extract of Arctotis arctotoides (Asteraceae) on the Growth and Ultrastructure of Some Opportunistic Fungi Associated with HIV/AIDS Wilfred M. Otang 1, Donald S. Grierson 1,* and Roland N. Ndip 1,2 1 School of Biological and Environmental Sciences, Faculty of Science and Agriculture, University of Fort Hare, P/Bag X1314, Alice 5700, South Africa; E-Mails: wilfredotang5@ (W.M.O.); RNdip@ufh.ac.za (R.N.N.) 2 Department of Biochemistry and Microbiology, Faculty of Science, University of Buea, Buea Box 63, Cameroon * Author to whom correspondence should be addressed; E-Mail: dgrierson@ufh.ac.za; Tel.: +27-0-40-602-2321; Fax: +27-0-86-628-2409. Received: 18 October 2011; in revised form: 23 November 2011 / Accepted: 24 November 2011 / Published: 9 December 2011 Abstract: In this study, the effect of the acetone extract of Arctotis arctotoides (L.f.) O. Hoffm. (Asteraceae) on the growth and ultrastructure of some opportunistic fungi associated with HIV/AIDS was analyzed by means of scanning electron microscope (SEM). Remarkable morphological alterations in the fungal mycelia which were attributed to the loss of cell wall strength ranged from loss of turgidity and uniformity, collapse of entire hyphae to evide