95例SARS患者的Th2细胞因子反应及其临床意义3.PDF

95 例 SA RS 患者的 Th2 细胞因子反应及其临床意义 1 2 2 1 2 2 2 1 黄嘉凌 ,段朝晖 ,罗小红 ,吴立志 ,檀卫平 , 闽　军 ,黄 　健 ,刘然义 , 1 1 1 1 黄必军 ,李 　焱 , 曾益新 ,黄文林 ( 1. 中山大学肿瘤防治中心 ,华南肿瘤学国家重点实验室 ,广州 510060 ;2 . 中山大学第二附属医院 ,广州 5 10 120) Predominance of Th2 Cytokine Response at Acute Phase in 95 Patients with SA RS and its Cl inical Signif icance HU AN G J ialin g1 , DU AN Zhaohui2 , L U O Xiaoho ng2 , WU Lizhi1 , TAN Weipin g2 , M IN J un2 , HU AN G J ian2 , L IU Ranyi1 , HU AN G Bij un1 , L I Yan1 , ZEN G Yixin1 , HU AN G Wenlin1 ( 1. S t ate Key L aboratory f or Oncol ogy i n S out h Chi na , Cancer Center of S un Yatsen Uni vers ity , Guang z hou , 5 10060 , Chi na; ) 2 . The S econ d A f f i l i ate d H osp it al of S un Yatsen Uni vers ity , Guang z hou 510 120 , Chi na Abstract : Thi s st udy wa s de signed to inve stigat e dynamic s of cyto kine s in acut e an d convale scent p atient s wit h Severe acut e re sp iratory syndro me ( SA R S) . The serum level s of cyto kine s ( IL2 , γ β β) IL4 , IL8 , int erleukin10 , IFN , TN F and T GF in 95 healt hy wor ker s wit h SA R S in our ho spit al were mea sured by EL ISA . Phenot yp e s of p erip heral lymp hocyt e s were analyzed by flow cyto met ry in acut e p ha se , co mp ared wit h t ho se of healt hy volunt eer s. The re sult s showed t hat γ serum level of IFN showed no significant chan ge during t he w hole p erio d of SA R SCoV at t ack , and IL2 lev