类风湿关节炎.ppt

正常手关节片第31页,共34页，2024年2月25日，星期天类风湿的膝关节病变第32页,共34页，2024年2月25日，星期天类风湿-不可忽视的疾病第33页,共34页，2024年2月25日，星期天*感谢大家观看第34页,共34页，2024年2月25日，星期天**1.SanghaO.Epidemiologyofrheumaticdiseases.Rheumatology.2000;39(suppl2):3-12.2.MacGregorAJ,SilmanAJ.Classificationandepidemiology.In:KlippelJH,

DieppePA,eds.Rheumatology.Vol1.2nded.London,UK:Mosby;1998:2.1-2.6.Slide3Notes.RheumatoidArthritis:EpidemiologyRAaffectsabout1%oftheglobaladultpopulation.1TheannualincidenceofRAisestimatedtobe0.1to0.2per1000inmalesand0.2to0.4per1000infemales.2TheincidenceandprevalenceofRAare2to3timeshigherinwomenthaninmen.1Thediseasehasbeenfoundaroundtheworldinmanydifferentracesandcultures.2ThepeakageofonsetofRAisbetween45and65years.2**1.AlarcónGS.Epidemiologyofrheumatoidarthritis.RheumDisClinNorthAm.1995;21:589-604.2.WolfeF,HawleyDJ.Thelongtermoutcomesofrheumatoidarthritisworkdisability:Aprospective18-yearstudyof823patients.JRheumatol.1998;25:2108-2117.3.PincusT.Theunderestimatedlongtermmedicalandeconomicconsequencesofrheumatoidarthritis.Drugs.1995;50(suppl1):1-14.Slide5Notes.RheumatoidArthritis:SocialandPsychologicalBurdenRAstrikesmenandwomenintheprimeoflife,impairingtheirphysicalfunctioning,ofteninterferingwiththeirabilitytoearnaliving,andevenshorteningtheirsurvival.1Within2yearsofdiagnosis,patientsusuallyexperiencemoderatedisability,andafter10years,theyareseverelydisabled.Approximately30%ofpatientsareunabletoworkwithin10yearsofdiseaseonset.2Inadditiontocausingpainandfatigue,RAcanpromotefeelingsofhelplessness,lossofself-sufficiency,anddepressionbecauseofitsdisablingeffects.Patientsoftenexperiencepsychologicaldistressduetotheirincreasingrelianceonhelpfromothers.3PatientswhohaveRAmaynotbeabletofulfillvarioussocialr