异腈参与多组分反应新进展.pdf

Studies in Synthetic Chemistry 合成化学研究, 2014, 2, 11-22 Published Online March 2014 in Hans. /journal/ssc /10.12677/ssc.2014.21002 New Progresses of Multicomponent Reactions Based on Isocyanides * Wenjing Jin, Guang Han, Xinwei He , Kai Hu, Yongjia Shang The Key Laboratory of Functional Molecular Solids Ministry of Education, College of Chemistry and Materials Science, Anhui Normal University, Wuhu * Email: xinweihe@ th th st Received: Feb. 4 , 2014; revised: Feb. 26 , 2014; accepted: Mar. 1 , 2014 Copyright © 2014 by authors and Hans Publishers Inc. This work is licensed under the Creative Commons Attribution International License (CC BY). /licenses/by/4.0/ Abstract This paper reviewed the new progresses of the multicomponent reactions based on isocyanides to synthesize the heterocyclic compounds, and mainly introduced some new reactions of the Ugi multicomponent reactions. The request of substrates, reaction conditions, selectivity, yield and mechanism were investigated in detail. Meanwhile, a brief introduction of some new Passerini multicomponent reactions was given. New breakthroughs in this field were intensely expected. Keywords Isocyanides, Multicomponent Reactions, Combinational Chemistry, Heterocyclic Compounds 异腈参与的多组分反应新进展 * 靳文静，韩 光，何心伟 ，胡 凯，商永嘉 安徽师范大学，化学与材料科学学院，功能分子固体教育部重点实验室，芜湖 * Email: xinweihe@ 收稿日期：2014年2月4 日；修回日期：2014年2月26 日；录用日期：2014年3月1 日 摘 要 本文综述了异腈参与的多组分反应合成一些杂环化合物的最新研究进展，主要介绍了异腈参与的Ugi多组 *通讯作者。 11 异腈参与的多组分反应新进展 分反应的几种新型反应，详细地介绍了各种反应对