盐酸环丙沙星片剂体内药动学参数测定.pdf
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集尿时间间隔时间（△t）htc尿量V吸光度A尿药浓度C（mg/ml）
02000.1630.1072471
110.52000.2460.1480582
211.52000.2760.1628092
4232000.2720.1608424
6252000.2190.1347823
937.52000.1960.1234732
12310.52000.2180.1342906
15313.52000.1870.1190479
4
3.5
3
2.5
2系列1
1.5
1
0.5
0
0246810121416
尿药量△X平均尿药速度（△X/△t）mg/mlln(△X/△t)t时排泄药量（Xu）mgXu∞-Xu
21.4494221.44942196.6608
29.6116429.611643.38816752751.06106167.0491
32.5618432.561843.48314105183.6229134.4873
32.1684816.084242.777839911115.79138102.3188
26.9564613.478232.601075791142.7478475.36234
24.694648.2315466672.107973927167.4424823.80958
26.858128.9527066672.191955907194.300623.80958
23.809587.9365266672.071475732218.11018
6y=-0.193x+5.31
R²=0.949
5
4
系列1
3
线性(系列
2
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