体素内不相干运动扩散加权成像对青年腰椎间盘早期退变定量分析的.docx

体素内不相干运动扩散加权成像对青年腰椎间盘早期退变定量分析的研究

陈芳胡明哲吴海陈耀孟朱佩佩

[关键词]?腰椎间盘退变；Pfirrmann分级；体素内不相干运动扩散加权成像；磁共振成像

[中图分类号]?R445.2??????[文献标识码]?A????[DOI]?10.3969/j.issn.1673-9701.2024.12.005

Quantitative?analysis?of?early?lumbar?disc?degeneration?in?young?adults?by?intravoxel?incoherent?motion?in?body?diffusion-weighted?imaging

CHEN?Fang，?HU?Mingzhe，?WU?Hai，?CHEN?Yaomeng，?ZHU?Peipei

Department?of?Imaging，?Wenzhou?Peoples?Hospital，?Wenzhou?325000，?Zhejiang，?China

[Abstract]?Objective?To?explore?the?predictive?value?of?slow?apparent?diffusion?coefficient?（ADCslow），?fast?apparent?diffusion?coefficient?（ADCfast）?and?perfusion?fraction?（f）?value?of?intravoxel?incoherent?motion?in?body?diffusion-weighted?imaging?（IVIM-DWI）?sequence?in?early?lumbar?disc?degeneration?in?young?people.?Methods?The?IVIM-DWI?technique?was?used?as?quantitative?magnetic?resonance?imaging?for?120?patients?（596?lumbar?intervertebral?discs）?with?lower?back?pain?included?in?Wenzhou?Peoples?Hospital.?The?ADCslow，?ADCfast?and?f?values?of?all?lumbar?intervertebral?discs?were?measured，?and?then?they?were?divided?into?3?groups?according?to?the?Pfirrmann?grading?standard.?SPSS?20.0?statistical?software?was?used?to?analyze?the?data.?Results?The?ADCfast?value?has?statistical?significance?in?distinguishing?the?lumbar?intervertebral?discs?of?each?group：?The?area?under?the?curve?（AUC）?of?the?normal?group?vs.?the?early?degenerative?group?was?0.766，?with?a?sensitivity?of?64.2%?and?a?specificity?of?78.5%;?The?AUC?of?the?normal?group?vs.?the?mid?to?late?stage?degenerative?group?was?0.822，?with?a?sensitivity?of?67.9%?and?a?specificity?of?91.3%;?The?AUC?of?the?early?degeneration?group?vs.?the?middle?and?late?stage?degeneration?group?was?0.797，?with?a?sensitivity?of?62.1%?and?a?specificity?of?92.1%.?The?ADCslow?value?has?statistical?significance?in?distinguishing?the?lumbar?intervertebral?discs?of?each?group：?AUC=0.707?in?the?normal?group?vs.?the?early?degenerative?group，?with?a?sensitivity?of?83.6%?and?a?specificity?of?61.0%;?The?