乳腺癌新辅助化疗后腋窝转移淋巴结病理完全缓解的预测因素及预后.docx

乳腺癌新辅助化疗后腋窝转移淋巴结病理完全缓解的预测因素及预后分析

徐琴袁军钱萍袁琳娜马祯一张自然

[关键词]?乳腺癌；新辅助化疗；腋窝淋巴结；病理完全缓解

[中图分类号]?R655????[文献标识码]?A????[DOI]?10.3969/j.issn.1673-9701.2024.05.007

Predictors?and?prognostic?analysis?of?pathological?complete?response?of?axillary?metastatic?lymph?nodes?after?neoadjuvant?chemotherapy?in?breast?cancer

XU?Qin1，?YUAN?Jun2，?QIAN?Ping1，?YUAN?Linna3，?MA?Zhenyi1，?ZHANG?Ziran4

1.Department?of?Pathology，?Jiaxing?Hospital?of?Traditional?Chinese?Medicine?affiliated?to?Zhejiang?Chinese?Medicine?University，?Jiaxing?314000，?Zhejiang，?China;?2.Department?of?Pathology，?Jiaxing?Maternity?and?Child?Health?Care?Hospital，?Jiaxing?314000，?Zhejiang，?China;?3.Department?of?Pathology，?The?First?Hospital?of?Jiaxing，?Jiaxing?314000，?Zhejiang，?China;?4.Department?of?Breast?Diseases，?Jiaxing?Maternity?and?Child?Health?Care?Hospital，?Jiaxing?314000，?Zhejiang，?China

[Abstract]?Objective?To?investigate?the?clinicopathological?factors?associated?with?pathological?complete?response?（pCR）?of?axillary?metastatic?lymph?nodes?in?breast?cancer?patients?after?neoadjuvant?chemotherapy?（NAC），?and?to?analyze?the?postoperative?survival.?Methods?A?total?of?116?patients?with?breast?cancer?with?axillary?lymph?node?metastasis?were?collected?from?Jiaxing?Hospital?of?TCM，?Jiaxing?Maternity?and?Child?Health?Care?Hospital?and?The?First?Hospital?of?Jiaxing.?Univariate?analysis?was?used?to?analyze?the?relationship?between?clinicopathological?factors?and?the?pCR?of?axillary?lymph?node?metastasis?in?breast?cancer?after?NAC.?Binary?Logistic?regression?was?used?to?analyze?the?independent?predictors?of?the?pCR?of?axillary?lymph?node?metastasis?in?breast?cancer?after?NAC.?Kaplan-Meier?survival?curve?was?used?to?analyze?the?disease-free?survival?rate?and?overall?survival?rate?of?patients?with?and?non-pCR?of?axillary?metastatic?lymph?nodes.?Results?Among?116?patients，?52?cases?of?axillary?metastatic?lymph?nodes?achieved?pCR?after?NAC，?accounting?for?44.83%.?Univariate?analysis?showed?that?age，?vascular?invasion，?pC