中药熏洗对类风湿关节炎有效性及安全性的Meta分析.pdf
循证护理2025年1月第11卷第2期(总第142期)·191·
·科研论著·
中药熏洗对类风湿关节炎有效性
及安全性的Meta分析
*
杨军,江帆,彭思敬,张传英
安徽中医药大学,安徽230012
EfficacyandsafetyofChinesemedicinefumigationinrheumatoidarthritis:aMeta-analysis
*
YANGJun,JIANGFan,PENGSijing,ZHANGChuanying
AnhuiUniversityofChineseMedicine,Anhui230012China
*CorrespondingAuthorZHANGChuanying,E⁃mail:chuanying512@
AbstractObjective:ToevaluatetheefficacyandsafetyoftraditionalChinesemedicinefumigationinthetreatmentofrheumatoid
arthritis.Methods:TherelevantstudiesoftraditionalChinesemedicinefumigationinthetreatmentofrheumatoidarthritiswereretrieved
fromCNKI,CBM,WanFangDatabase,VIP,PubMed,WebofScience,theCochraneLibrary,EMbaseandCINAHL.Thesearchperiod
wasfromtheestablishmentofthedatabasetoMay30,2024.RevMan5.4.1softwarewasusedforMeta-analysis.Results:Atotalof18
studieswereincluded,involving1540patients.TheresultsofMeta-analysisshowedthatcomparedwiththecontrolgroup,traditional
Chinesemedicinefumigationcouldimprovethetotaleffectiverateofpatients(OR=2.94,95%CI2.10-4.12,P0.00001),reducethe
levelsofVASscore(MD=-1.02,95%CI-1.14--0.90,P0.00001),ESR(MD=-11.38,95%CI-12.26--10.49,P0.00001),
CRP(MD=-6.46,95%CI-7.84--5.07,P0.00001)andRF(MD=-39.22,95%CI-57.28--21.16,P0.00001),reducethe
numberofjointswelling(MD=-1.28,95%CI-1.38--1.18,P0.00001),jointtenderness(MD=-1.74,95%CI-1.94--1.53,P
0.00001)andmorningstiffnessofpatients(MD=-10.32,95%CI-11.52--9.12,P0.00001).Therewasnosignificantdifferencein
theincidenceofadversereaction