硫酸镁联合硝苯地平治疗妊娠高血压的效果分析.pdf
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硫酸镁联合硝苯地平治疗妊娠高血压的效果分析
任雁
132011北华大学附属医院妇产科,吉林吉林
doi:10.3969/j.issn.1007-614x.2025.06.017
摘要目的:分析硫酸镁联合硝苯地平治疗妊娠高血压的效果。方法:选取2019年1月—2024年12月北华大学附属
医院收治的妊娠高血压患者94例作为研究对象,随机分为对照组与试验组,每组47例。对照组给予硝苯地平治疗,试验
组在对照组基础上给予硫酸镁治疗。比较两组血压、心率、检验指标、不良妊娠结局发生情况。结果:治疗前,两组收缩
压、舒张压、心率比较,无统计学差异(P>0.05);治疗后,两组收缩压、舒张压、心率降低,且试验组低于对照组(P<0.05)。
试验组不良妊娠结局总发生率低于对照组(P=0.014)。治疗前,两组尿素氮、血液黏度、尿蛋白水平比较,无统计学差异
(P>0.05);治疗后,两组尿素氮、血液黏度、尿蛋白水平降低,且试验组低于对照组(P<0.05)。结论:硫酸镁联合硝苯地
平治疗妊娠高血压的效果显著,可降低血压和心率,改善检验指标,减少不良妊娠结局。
关键词妊娠高血压;硫酸镁;硝苯地平
中图分类号R714文献标识码A
EffectAnalysisofMagnesiumSulfateCombinedwithNifedipineinTreatmentofGestationalHypertension
RenYan
DepartmentofObstetricsandGynecology,AffiliatedHospitalofBeihuaUniversity,Jilin132011,JilinProvince,China
AbstractObjective:Toanalyzetheeffectofmagnesiumsulfatecombinedwithnifedipineinthetreatmentofgestational
hypertension.Methods:Atotalof94patientswithgestationalhypertensionadmittedtotheAffiliatedHospitalofBeihuaUniversity
fromJanuary2019toDecember2024wereselectedasthestudysubjects.Theywererandomlydividedintocontrolgroupand
experimentalgroup,with47casesineachgroup.Thecontrolgroupwastreatedwithnifedipine,whiletheexperimentalgroupwas
treatedwithmagnesiumsulfateonthebasisofthecontrolgroup.Thebloodpressure,heartrate,testindicators,andincidenceof
adversepregnancyoutcomeswerecomparedbetweenthetwogroups.Results:Beforetreatment,therewasnostatistically
significantdifferenceinsystolicbloodpressure,diastolicbloodpressureandheartratebetweenthetwogroups(P0.05).After
treatment,thesystolicbloodpressure,diastolicbloodpressureandheartrateinthetwogroupsdecreased,andtheseparametersin
theexperimentalgroupwerelowerthanthoseinthecontrolgroup(P0.05).Theoverallincidenceofadversepregnancyoutcomes
in