降香挥发油包合工艺研究.pdf

新疆医科大学学报 JOURNAL OF XINJIANG M EDICAL UNIVERSITY 2010 Jul. , 33( 7) 793 降香挥发油包合工艺研究 李 茜1* , 赵生俊1 , 蒋宇宁1, 李晓雯2 ( 1新疆医科大学中医医院药学部, 新疆 乌鲁木齐 830000; 2 乌鲁木齐市仓房沟路 95 号 93886 部队医院, 新疆 乌鲁木齐 830005) 摘要: 目的 优化降香挥发油 B2环糊精(B2CD) 包合的制备工艺。 方法 考察挥 发油利用率, 用正 交设计法 对降香挥发油 B2CD 包合工艺进行优选。 结果 降香挥发油与 B2CD 包合物最佳制备工 艺是挥发油 (ml) B B2环糊 精( g) 为 1B 5, 在 40e 下包合 60 min。结论 所选取的提取降香 挥发油较好, 说明 本制备工艺 适合降香 挥发油包 合物的制备。 关键词: 降香挥发油; B2环糊精包合物; 制备工艺 中图分类号: R9 文献标识码 : A 文章编号: 100925551(2010) 0720793204 Studise on preparation technology for the inclusion of Dalbergia odorif ent T. Chen Essential oil2B2cyclodextrin LI Qian, ZHAO Sheng2jun, JIANG Yu2ning, et al ( Aff ilia ted T ra ditional Chinese Medical H osp ital , Xinj ia ng Medical University , Urumqi 830000, China) Abstract: Objective T o optimize the preparation technology for the inclusion of Da lber gia od or if ent T . Chen Essential oil2B2cyclodextrin (B2CD) . Methods It was studied with Or thogonal design on the extrac2 tion of Essential oil of Dalbergia odorif ent T. Chen andB2cyclodextrin inclusion compound. Results T he optimum preparation technology for the inclusion compound of Dalberg ia odor if ent T. Chen Essential oil2 B2CD was as follows: essential oils BB2CD was 1 B 5, the temperature and time was 40 e for 90 mins. Con2 clusion The method can easily prepar e and produce Dalber gia odor if ent T. Chen Essential oil2B2cyclodex2 trin (B2CD) on a large scale. Key wor ds: essential oil of Dalberg ia odorif ent T; B2CD inclusion; preparation technics 天香丹胶囊由红景天、丹参、降香等药组成, 具 状物, 它可提高血小板 cAMP 含量, 具有抗血栓形 有益气补虚、和血通络、化??散结的功效, 临床主要 成的作用[ 3] 。多与丹参、川芎等活血化瘀药配伍, 用 用于治疗心气虚损, 心脉瘀阻所致