新西兰双氰胺检测方法.doc

Determination of Dicyandiamide, Cyanuric Acid and Melamine in Dairy Products by High Performance Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS) Confidentiality Statement This method is the property of AsureQuality Ltd. and cannot be copied, used or distributed without the written permission of the Wellington Laboratory Business Manager. Safety and Health MSD sheets of all chemicals, solvents and standards must be understood by the analyst before commencing the method. Avoid inhaling vapors or chemicals. Use the assigned protective clothing and equipment at all times. Ensure that you are familiar with the location of fire extinguishers, first aid kit and any safety equipment that may be required. Refer to the Laboratorys Hazard Register for Significant Hazards identified and the control methods specified to minimise these hazards. Specific Hazards and Control Methods Not Applicable. definitions ABBREVIATIONS DCD Dicyandiamide HPLC High Performance Liquid Chromatography IR Ion Ratio IS Internal Standard KTP Key Technical Personnel LC-MS/MS Liquid Chromatography Tandem Mass Spectrometry LIMS Laboratory Information Management System LOD Limit of Detection LOQ Limit (or Level) of Quantification LOR Limit of Reporting M Molecular Mass MRM Multiple Reaction Monitoring MSD sheets Material Safety Data sheets PVDF Polyvinylidene Fluoride Q1 Quantification ion Q2 Secondary quantification (check) ion QC Quality Control RR Relative Response RS Recovery Standard RT Retention Time SOP Standard Operating Procedure U Uncertainty of Measurement with 95% confidence interval WS Working Standard DEFINITION OF TERMS Analyte: This is the component of a sample that has to be detected, identified and quantified. The term “analyte” includes, where appropriate, derivatives formed from the analyte during analysis. Analytical samples: Samples required to be analysed quantitatively for the presence of target analytes. External Standard: