非高密度脂蛋白胆固醇及冠心病相关性探究.doc

非高密度脂蛋白胆固醇及冠心病相关性探究【摘要】 目的 探讨非高密度脂蛋白胆固醇(nonHDLC)与冠心病的关系。 方法 对连续372例冠脉造影患者的血脂及冠脉造影结果回顾性分析。冠脉造影阴性114例为对照组，冠脉造影阳性258例为冠心病组，冠心病组根据冠脉病变支数分为单支病变组(104例)和双支及三支病变组(154例)，对以上各组的血脂及nonHDLC结果进行比较。结果 ①与冠脉造影阴性组比较，冠脉造影阳性组nonHDLC水平明显增高。②在冠脉造影阳性组，nonHDLC水平随病变支数增加而上升。结论 nonHDLC与冠状动脉粥样硬化病变关系密切，控制nonHDLC在冠心病的防治中有重要意义。 【关键词】 非高密度脂蛋白胆固醇；冠心病 Relation between nonhigh density lipoproteincholesterol and coronary heart disease ZHANG Tiexu, LI Qingmin, FAN Jurong, et al.Department of Cardiology, The First Peoples Hospital of Pingdingshan City; Pingdingshan 467000,China 【Abstract】 Objective To investigate the relation between nonhigh density lipoproteincholesterol (nonHDLC) and coronary heart disease Methods Totally 372 cases who underwent coronary angiography (CAG) were divided into CHD group who was positive in CAG (n=258) and controlled group who was negative in CAG (n=114), comparing for the blood lipid and nonHDLC between two groups CHD group were divided into single branch group and two or three branch group, comparing for the blood lipid and nonHDLC between two groups Results ①Comparing to the controlled group, the level of nonHDLC in CHD group increased with statistical significance(P005)②Comparing to the single branch group, the levels of nonHDLC in two or three branch group increased with statistical significance(P005) Conclusion Serum nonHDLC is related to the severity of coronary artery lesions It is important to control the level of nonHDLC in order to treat and prevent coronary heart disease. 【Key words】 Non high density lipoproteincholesterol; Coronary heart disease 高脂血症是动脉粥样硬化的发生、发展中的重要危险因素，调脂治疗是目前临床上防治动脉硬化的重要手段，低密度 -------------------------------------------------------------------------------- 作者单位：467000 河南省平顶山市第一人民医院心内三科(张铁须 李庆民 王强),干部病房(范聚荣) 脂蛋白胆固醇(low density lipoprotein，LDLC)是调脂治疗的主要目标。近年来，非高密度脂蛋白胆固醇(non high density lipoproteincholesterol，nonHDLC)渐渐受到了临床的关注。 -----------------------------------------------