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血栓弹力图的临床应用_附28例疑似凝血异常患者检测结果分析_.doc

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安 徽 医 药 Anhui Medical and Pharmaceutical Journal 2014 Jul;18(7) ·1275· 血栓弹力图的临床应用(附 28 例疑似凝血异常患者检测结果分析) 卞茂红,朱帮强,钟 涛,程 越,胡海亮,马文娟,张循善 (安徽医科大学第一附属医院输血科,安徽 合肥 230022) 摘要:目的 分析 28 例易发凝血功能紊乱疾病患者的血栓弹力图(thrombelastography,TEG)检测结果参数及图形变化,探讨其 在诊治中的应用价值。方法 选择 28 例凝血功能易发紊乱的疾病患者和 26 例健康志愿者,抽取抗凝血,按 TEG 检测仪标准 操作规程由专人进行 TEG 检测。结果 28 例患者的 TEG 检测中 R 时间、K 时间、α 角及最大振幅 MA 的异常比例分别为 46. 4% 、14. 3% 、21. 4% 和 14. 3%;与 26 例健康志愿者 TEG 检测结果相比较,差异有显著性。结论 TEG 可以反映易发凝血功能 紊乱疾病患者的凝血全貌,及时准确判断患者凝血功能,指导临床治疗 。 关键词:凝血异常;血栓弹力图;应用 doi: 10. 3969 /j. issn. 1009 - 6469. 2014. 07. 023 Clincal application of thrombelas-tography (TEG)( 28 patients with probable abnormal coagulation profiles were tested and analyzed) BIAN Mao-hong,ZHU Bang-qiang,ZHONG Tao, et al (Department of Transfusion,The First Affiliated Hospital of Anhui Medical University,Hefei 230022,China) Abstract: Objective To detect and analyze twenty-eight patients with probable abnormal coagulation profiles by thrombelas-tography (TEG), and to explore the clinical value. Methods Twenty-eight patients with suspected abnormal coagulation were selected and their anticoagulant blood samples were withdrawn and tested by the standard operation procedure of TEG. Results Among the four parame- ters,abnormal proportions of the R time,K time, (MA)were 46. 4% ,14. 3% ,21. 4% and 14. 3% , angle α and maximum amplitude re- spectively. There were significant differences in the TEG results in comparison with healthy volunteers. Conclusions TEG can reflect the coagulation profiles of patients likely to have coagulopathy, the detection of which will be valuable in timely therapies and therapeu- tic evaluation. Key words:miocardial infarction;disorders of hemostasis;thrombelastography; application 冠心病、心肌梗死和术后不明原因的出血等疾病,其发 1. 3 方法 检测应用全血复钙法:患者采用枸橼酸钠抗凝 生机制复杂,但与血液凝固异常、血小板黏附增加、纤溶活 的静脉血标本 2 mL,充分混匀,吸取 1 mL 加入至室温复温 性低下等密切相关,且对其发生和发展起着十分重要的作 30 min 后的高岭土试剂杯,缓慢上下颠倒混匀 5 次,在室温 用。血栓弹力图(thrombelastography,TEG) 是应用血栓弹力 下放置 5 min 后备用。将一次性普通测试杯装入仪器的检 图仪描记血液凝固所形成的全过程,它以图形的形式观察 测架,
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