富含血小板血浆在骨关节疾病及骨骼组织修复中的应用.pdf

. . 中国骨与关节杂志 2013 年７月第２卷第７期 Chinese Journal of Bone and Joint, July 2013, Vol 2, No.7 407 . 综述 Review . 血小板浓缩物在骨关节病和运动损伤疾病中的应用 李晋　王文波　谢燕霞　阎影 DOI: 10.3969/j.issn.2095-252X.2013.07.012　　中图分类号：R684, R318 m 作者单位：100094 北京，干细胞与再生医学研究所中健医疗集团 ( 李晋，王文波，谢燕霞，阎影 )； o 　　　　　64108 堪萨斯，密苏里大学堪萨斯医学院癌症研究所 ( 阎影 ) 通信作者：阎影，Email: yany@umkc.edu c ） . Platelet Concentrate Therapy in the Osteoarthropathy and Sport Injury LI Jin,WANG Wen-bo, XIE Yan-xia, YAN 4 权 Ying. Institute for Stem Cell and Regenerative Medicine of Zhongjian Healthcare Group, Beijing 100094, PRC; Saint 0 Lukes Cancer Institute and School of Medicine, UMKC, Kansas City 64108, USA 3 版 Abstract Platelet concentrate ( PC ) for surgical use is an evolution of the fibrin glue technologies used since 【 】 many years. The initial concept of these preparations was to concentrate platelets and their growth factors and activate b （ it into a fibrin gel on a surgical site, in order to improve local healing. The platelets contain alpha granules that are rich in several growth factors, such as platelet-derived growth factor, vascular endothelial growth factor, transforming j 部 growth factor-β, insulin-like growth factor, and epidermal growth factor, which play the essential roles in tissue healing and regeneration mechanisms. The relative ease of obtaining and preparation, convenience and applicability