biodegradable cellulose-based hydrogels design and applications可生物降解的纤维素基水凝胶的设计和应用.pdf

Materials 2009, 2, 353-373; doi:10.3390/ma2020353 OPEN ACCESS materials ISSN 1996-1944 /journal/materials Review Biodegradable Cellulose-based Hydrogels: Design and Applications Alessandro Sannino*, Christian Demitri and Marta Madaghiele Department of Engineering for Innovation, University of Salento, Via per Monteroni, 73100 Lecce, Italy; E-Mails: christian.demitri@unile.it (C.D.); marta.madaghiele@unile.it (M.M.) * Author to whom correspondence should be addressed; E-Mail: alessandro.sannino@unile.it; Tel. +39-0832-297-259; Fax: +39-0832-297-240 Received: 28 February 2009; in revised form: 3 April 2009 / Accepted: 9 April 2009 / Published: 16 April 2009 Abstract: Hydrogels are macromolecular networks able to absorb and release water solutions in a reversible manner, in response to specific environmental stimuli. Such stimuli-sensitive behaviour makes hydrogels appealing for the design of ‘smart’ devices, applicable in a variety of technological fields. In particular, in cases where either ecological or biocompatibility issues are concerned, the biodegradability of the hydrogel network, together with the control of the degradation rate, may provide additional value to the developed device. This review surveys the design and the applications of cellulose-based hydrogels, which are extensively investigated due to the large availability of cellulose in nature, the intrinsic deg