sirt1—a sensor for monitoring self-renewal and aging process in retinal stem cellssirt1-a传感器监测在视网膜干细胞自我更新和老化过程.pdf

Sensors 2010, 10, 6172-6194; doi:10.3390/s100606172 OPEN ACCESS sensors ISSN 1424-8220 /journal/sensors Article SirT1—A Sensor for Monitoring Self-Renewal and Aging Process in Retinal Stem Cells Chi-Hsien Peng 1,3,6, Yuh-Lih Chang 2,5,†, Chung-Lan Kao 4,6,†, Ling-Ming Tseng 2,4,6,†, Chih-Chia Wu 3,6, Yu-Chih Chen 2,6,†, Ching-Yao Tsai 6,7, Lin-Chung Woung 6,7, Jorn-Hon Liu 8, Shih-Hwa Chiou 2,5,6,* and Shih-Jen Chen 3,4,6,* 1 Department of Ophthalmology, Shin Kong Wu Ho-Su Memorial Hospital and Fu-Jen Catholic University, Taipei 11101, Taiwan; E-Mail: chpeng1008@ (C.-H.P.) 2 Department of Medical Research and Education, Taipei Veterans General Hospital, 201 Shih-Pai, Road, Section 2, Taipei 11217, Taiwan; E-Mails: ylchang@.tw (Y.-L.C.); ycchen@.tw (Y.-C.C.); 3 Department of Ophthalmology, Taipei Veterans General Hospital, 201Shih-Pai, Road, Section 2, Taipei 11217, Taiwan; E-Mail: ccwu@.tw (C.-C.W) 4 Department of Physical Medicine Rehabilitation and Surgery, Taipei Veterans General Hospital, 201Shih-Pai, Road, Section 2, Taipei 11217, Taiwan; E-Mails: clkao@.tw (C.-L.K); lmtseng@.tw (L.-M.T) 5 Institute of Pharmacology, National Yang-Ming University, No. 155, Sec 2, Linong Street, Taipei 11221, Taiwan 6 Institute of Clinical Medicine, National Yang-Ming University, No. 155, Sec 2, Linong Street, Taipei 11221, Taiwan; E-Mails: DAC58@.tw (C.-Y.T.); Dac91@.tw (L.-C.W.) 7 Department of Ophthalmology, Taipei City Hospital, Taipei, Taiwan 8 Department of Ophthalmology, Cheng Hsin General Hospital, Taiwan; E-Mail:jhliu@.tw (J. -H.L) † These authors contribut