study on ph effect in process of an entero-gastric fiber-optic sensor design研究ph值效应entero-gastric光纤传感器设计的过程.pdf

Sensors 2002, 2, 447-454 sensors ISSN 1424-8220 © 2002 by MDPI /sensors Study on pH Effect in Process of an Entero-gastric Fiber-optic Sensor Design 1,* 1 2 1 Chen Guo-ping , Xia Rong-min , Gong Jun and Shou Wen-de 1 Department of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai 200030, China. Tel.86-21 Fax 86-21 E-mail: gpchenapple@ 2 Department of Digestion, Second Hospital of Xi’an Jiaotong University, Xi’an 710004,China * Author to whom correspondence should be addressed. Received: 28 October 2002 / Accepted: 15 November 2002 / Published: 30 November 2002 Abstract: The pH effect on design of a fiber optic sensor newly developed for monitoring entero-gastric reflux is investigated. The research has been carried out by utilizing the sensor to measure characteristic absorption of bilirubin standard solution (used as a calibrator) at different pH values from about 1 to 8. The results show explicitly that the estimation error according to the calibration curves with pH 7 is significantly lower than that at alkaline pH values. Compared with the in vitro experimental data, the optimum pH range for entero-gastric reflux analysis is proposed to be between 5-6. The possible reasons for estimation error of the fiber optic sensor are given in detail. Keywords: Fiber optic sensor, Bilirubin, pH, Entero-gastric reflux Intro