context matters the illusive simplicity of macaque v1 receptive fields环境问题虚幻的猕猴v1的简单接受字段.pdf

Context Matters: The Illusive Simplicity of Macaque V1 Receptive Fields 1,2 . 3,4,5. 4 4 2,6 Robert Haslinger * , Gordon Pipa , Bruss Lima , Wolf Singer , Emery N. Brown , Sergio Neuenschwander4,7 1 Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, Massachusetts, United States of America, 2 Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America, 3 Department of Neuroinformatics, University of Osnabruck, Osnabruck, Germany, 4 Max-Planck Institute for Brain Research, Department of Neurophysiology, Frankfurt am Main, Germany, 5 Frankfurt Institute for Advanced Studies, Frankfurt am Main, Germany, 6 Department of Anesthesia and Critical Care, Massachusetts General Hospital, Boston, Massachusetts, United States of America, 7 Brain Institute, Federal University of Rio Grande do Norte, Natal, Brazil Abstract Even in V1, where neurons have well characterized classical receptive fields (CRFs), it has been difficult to deduce which features of natural scenes stimuli they actually respond to. Forward models based upon CRF stimuli have had limited success in predicting the response of V1 neurons to natural scenes. As natural scenes exhibit complex spatial and temporal correlations, this could be due to surround effects that modulate the sensitivity of the CRF. Here, instead of attempting a forward model, we quantify the importance of the natural scenes surround for awake macaque monkeys by modeling it non-parametrically. We also quantify the influence of two forms of trial to trial variability. The first is related to the neuron’s own spike history. The second is related to ongoing mean field