恶心呕吐- 课件.ppt

泸沽湖黄昏 泸沽湖?摩梭女 玉龙雪山?雪月 * Constipation Shanghai Second Medical university Renji clinical medical college Background Constipation Is a Constellation of Symptoms Most commonly reported symptoms Hard, lumpy stools Increased straining Infrequent bowel movements Sensation of incomplete evacuation Bloating/fullness Chronic constipation More persistent than intermittent or episodic Several months duration C Sandler RS, et al. Dig Dis Sci. 1987;32:841-845. n = 1128 Constipation Is More Than Just Infrequent Passage of Stool 53 Constipation symptoms reported most often Reduced Stool Frequency Is Not the Most Commonly Reported Symptom in Constipation EPOC = Epidemiology of constipation; BM = Bowel movement. 1. Stewart WF, et al. Am J Gastroenterol. 1999;94:3530-3540. 2. Paré P, et al. Am J Gastroenterol. 2001;96:3130-3137. Stewart (EPOC) 19991 Paré 20012 n = 1476 n = 1149 Constipation symptoms reported most often C Prevalence in the General Population 1. Stewart WF, et al. Am J Gastroenterol. 1999;94:3530-3540. 2. Drossman DA, et al. Dig Dis Sci. 1993;38:1569-1580. 3. Harris Interactive Study, Wave 2. Data on file. 4. Paré P, et al. Am J Gastroenterol. 2001;96:3130-3137. 53 Population n Criteria Prevalence, n (%) US1 10,018 Rome I 461 (4.6) US2 5430 Rome I 195 (3.6) US3 15,183 Rome II 2429 (16) Canada4 1149 Rome II 171 (14.9) China (18-70ys) ? RomeII ?(6.07) China(60ys) ? RomeII ?(15-20) Epidemiology Chronic constipation is common Slightly more common in women F/M ratio = range 1.3 to 2.5 (China=4:1) Affects all age groups Stewart WF, et al. Am J Gastroenterol. 1999;94:3530-3540. Paré P, et al. Am J Gastroenterol. 2001;96:3130-3137. Sandler RS, et al. Dig Dis Sci. 1987;32:841-845. C Constipation Affects All Age Groups 53 Canadian population. Paré P, et al. Am J Gastroenterol. 2001;96:3130-3137. N = 1149 n = 378 n = 367 n = 217 n = 187 Profile of a Typical Chronic Constipation Patient in My Practice Generally female Symptomatic for 10 yr Majority have tried lifest