达泊西汀治疗早泄的有效性系统评价_王亚波.pdf

( ) JOURNALOFPEKINGUNIVERSITY(HEALTHSCIENCES)　Vo.l42　No.4　Aug.20 10 ·4 25 · ·论著 · 达泊西汀治疗早泄的有效性系统评价 1, 2 1 1 3 1■ 王亚波 ,毛　宇, 魏　强 ,吴泰相 , 董　强 (1., 　61004 1;2.;3. ) [　] 目的:。方法: 1979 ～2009 Medline、EMbase、 Cochrane、、、CNKI, 《》 5 , , ReMan Meta, 。 结果: 5 (randomizedcontrolledtria,lRCT), 4 433 。 3 A, 2 B, (intraaginalejaculatorylatencytmi,e IELT)、 (patient-reportedglobalmipressionofchang,ePGI)、(satisfactionwithsexualintercours,eSWSI)、 (perceiedcontroloerejaculation, PCOE) (personaldistressrelatedtoejaculation, PDRE), 9 ～24 , Meta, IELT、SWSI PCOE 95% (CI) 1.38 (1.21, 1.55 )、0.55 (0.48, 0.62 ) 0.63 (0.4 9, 0.7 8), P 0.00 1; , PGI、SWS、IPCOE PDRE OR 95%CI 3.56 (2.60, 4.88)、3.85 (2.0 8, 7.10 )、2.87 (2.30, 3.58) 2.02 (1.69, 2.42 ), P0.00 1, 。 , 。结论:, , , , , 。 [] ;;Meta; [] R256.55　　[] A　　[] 167 1-167 X(2010 )04 -0425-08 do:i10.3969/.jissn.167 1-167 X.2010.04.015 Dapoxetineintreatmentofprematureejaculation:Asystematicreiew 1, 2 1 1 3 1■ WANGYa-bo, MAOYu, WEIQiang, WUTa-ixiang, DONGQiang (1.DeparmtentofUrology, WestChinaHospitalofSichuanUniersity, Chengdu61004 1, China;2.DeparmtentofUrolo- gy, TheFirstPeople sHospitalofLongQuanyiDistric;t3.ChineseCochraneCentr,eWestChinaHospitalofSichuanUn-i ersity) ABSTRACT　Objecti:eToassessstheeffectienessofdapoxetineinthetreatmentofprematureejacula- tion.Method:sBothEnglishandChinesestudiesinolingmenwithprematrueejaculationwhowere treatedwithdapoxetinefromtheCochraneLibrar,yMEDLINE, EMBASEandCNK,ICBM, VIPbetween 1979 and2009.wereincludedintherandomizedcontrolledtrials(RCTs)andthedataprocessedbyRe- Man.Result:sFieRCTsinoling4433 patientswereincludedintheMetaanalysi,sofwhich3 wereof gradeAand2 wereofgradeBaccordingtothequalityealuationofmethodology.Intraaginalejaculatory latencytmie(IELT), patient-reportedglo