1-(2,3-二氯苯基)哌嗪.pdf

Vo.l 13, No. 9 13 9 # 8# F ine and Specialty Chem icals 2005 5 6 1-( 2, 3-二氯苯基)哌嗪 李宁蔚 (东华大学, 上海 200051) : 2, 6-, 1 1-( 2, 3-), 4812% IRHNMR : 1-( 2, 3-); ; 2, 6- Syn th esis of 1-( 2, 3-D ich lorophenyl) p ip erazine LI N ing-w ei ( Donghua University, Shanghai 200051, China) A bstrac t: 1-( 2, 3-d ichlorophenyl) p iperazine is synthesized from 2, 3-d ichloron itrobenzene and piperazine by alkyla- tion, acidulation, reduction of n itro group, diazotization, substitution and hydrolys is reactionw ith the total yield of 4812% . 1 The structure of 1-( 2, 3-dich lorophenyl) piperazine is confirm ed by IR and HNMR. K ey w ord s: 1-(2, 3-d ichlorophenyl) piperazine; piperazine; 2, 3-d ichloron itrobenzene 1-( 2, 3-), C l H N H N) NH # H O, C 2 ( CH ) (CH ) NO 11, 22 2 2 2 3 2 2 3 2 , FeC l N C H N, CuCl 3 2 3 2 , , ,