the hellp syndrome clinical issues and management. a review临床上妊娠综合症临床问题和管理。.pdf

BMC Pregnancy and Childbirth BioMed Central Review Open Access The HELLP syndrome: Clinical issues and management. A Review 1 2 3 Kjell Haram , Einar Svendsen* and Ulrich Abildgaard Address: 1Department of Obstetrics and Gynaecology, Haukeland University Hospital, Bergen, Norway, 2Department of Pathology, The Gade Institute, Haukeland University Hospital, University of Bergen, Norway and 3Department of Haematology, Aker University Hospital, N-0514 Oslo, Norway Email: Kjell Haram - kjell.haram@broadpark.no; Einar Svendsen* - einar.svendsen@gades.uib.no; Ulrich Abildgaard - ulricha@ulrik.uio.no * Corresponding author Published: 26 February 2009 Received: 2 September 2008 Accepted: 26 February 2009 BMC Pregnancy and Childbirth 2009, 9:8 doi:10.1186/1471-2393-9-8 This article is available from: /1471-2393/9/8 © 2009 Haram et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background: The HELLP syndrome is a serious complication in pregnancy characterized by haemolysis, elevated liver enzymes and low platelet count occurring in 0.5 to 0.9% of all pregnancies and in 10–20% of cases with severe preeclampsia. The present review highlights occurrence,