生物信息学教学资料生物信息学常用数据库.pptx

一级数据库 数据库中的数据直接来源于实验获得的原始数据，只经过简单的归类整理和注释。 二级数据库 对原始生物分子数据进行整理、分类的结果，是在一级数据库、实验数据和理论分析的基础上针对特定的应用目标而建立的。;（1）美国生物技术信息中心的GenBank /Web/Genbank/index.html （2）欧洲分子生物学实验室的EMBL http://www.embl-heidelberg.de （3）日本遗传研究所的DDBJ http://www.ddbj.nig.ac.jp/;;4;Submissions to GenBank Many journals require submission of sequence information to a database prior to publication so that an accession number may appear in the paper. NCBI has a WWW form, called BankIt, for convenient and quick submission of sequence data. Sequin, NCBIs stand-alone submission software for MAC, PC, and UNIX platforms, is also available by FTP. When using Sequin, the output files for direct submission should be sent to GenBank by electronic mail. There are specialized, streamlined procedures for batch submissions of sequences, such as EST, STS, and HTG sequences. Updating or Revising a Sequence Revisions or updates to GenBank entries can be made at any time and can be accepted as BankIt or Sequin files or as the text of an e-mail message. Click on the link for more information about updating information on GenBank records. ;Access to GenBank GenBank is available for searching at NCBI via several methods. The GenBank database is designed to provide and encourage access within the scientific community to the most up to date and comprehensive DNA sequence information. Therefore, NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted. NCBI is not in a position to assess the validity of such claims, and therefore cannot provide comment or unrestricted permission concerning the use, copying, or distribution of the information contained in GenBank. New Developments NCBI is continuously developing new tools and enhancing existing ones to improve both submission and access to GenBank. The easiest way to keep abreast of these and other de