association of left ventricular mass with all-cause mortality, myocardial infarction and stroke左心室质量协会和全因死亡率,心肌梗塞和中风.pdf

Association of Left Ventricular Mass with All-Cause Mortality, Myocardial Infarction and Stroke 1,2 ´ 3 ´ ´ 1 ´ 1,2 Alberto Bouzas-Mosquera *, Francisco J. Broullon , Nemesio Alvarez-Garcıa , Jesus Peteiro , ´ 4, Alfonso Castro-Beiras 1,2 Vıctor X. Mosquera ˜ ˜ 1 Department of Cardiology, Hospital Universitario A Coruna, A Coruna, Spain, 2 Spanish Cooperative Cardiovascular Disease Research Network (RECAVA) - Instituto de ˜ ˜ Salud Carlos III, Madrid, Spain, 3 Department of Information Technology, Hospital Universitario A Coruna, A Coruna, Spain, 4 Department of Cardiac Surgery, Hospital ˜ ˜ Universitario A Coruna, A Coruna, Spain Abstract Background: Our aim was to assess the association of left ventricular mass with mortality and nonfatal cardiovascular events. Methodology/Principal Findings: Left ventricular mass was measured by echocardiography in 40138 adult patients (mean age 61.1 616.4 years, 52.5% male). The primary endpoint was all-cause mortality. Secondary endpoints included nonfatal myocardial infarction and nonfatal stroke. During a mean follow-up period of 5.663.9 years, 9181 patients died, 901 patients had a nonfatal myocardial infarction, and 2139 patients had a nonfatal stroke. Cumulative 10-year mortality was 26.8%, 31.9%, 37.4% and 46.4% in patients with normal, mildly, moderately