arabidopsis thaliana chromosome 4 replicates in two phases that correlate with chromatin state拟南芥染色体4复制与染色质状态的两个阶段.pdf

Arabidopsis thaliana Chromosome 4 Replicates in Two Phases That Correlate with Chromatin State 1. 2. 2 2¤a 4 Tae-Jin Lee , Pete E. Pascuzzi , Sharon B. Settlage , Randall W. Shultz , Milos Tanurdzic , Pablo D. 4¤b 5 6 6 5 1 Rabinowicz , Margit Menges , Ping Zheng , Dorrie Main , James A. H. Murray , Bryon Sosinski , 1 4 2 4 George C. Allen , Robert A. Martienssen , Linda Hanley-Bowdoin , Matthew W. Vaughn , William F. Thompson3* 1 Department of Horticultural Science, North Carolina State University, Raleigh, North Carolina, United States of America, 2 Department of Molecular and Structural Biochemistry, North Carolina State University, Raleigh, North Carolina, United States of America, 3 Departments of Plant Biology, Genetics, and Crop Science, North Carolina State University, Raleigh, North Carolina, United States of America, 4 Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, United States of America, 5 School of Biosciences, Cardiff University, Cardiff, Wales, United Kingdom, 6 Department of Horticulture and Landscape Architecture, Washington State University, Pullman, Washington, United States of America Abstract DNA replication programs have been studied extensively in yeast and animal systems, where they have been shown to correlate with gene expression and certain epigenetic modifications. Despite the conservation of core DNA replication proteins, little is known