synthesis and chromatography-free purification of pna-peo conjugates for the functionalisation of gold sensors合成和chromatography-free净化pna-peo配合functionalisation黄金的传感器.pdf

Molecules 2012, 17, 11026-11045; doi:10.3390/molecules170911026 OPEN ACCESS molecules ISSN 1420-3049 /journal/molecules Article Synthesis and Chromatography-Free Purification of PNA-PEO Conjugates for the Functionalisation of Gold Sensors 1 2 1 3 4 Monica Dettin , Davide Silvestri , Roberta Danesin , Erica Cretaio , Gianluca Picariello , Elisabetta Casarin 2, Agnese Sonato 5, Filippo Romanato 5 and Margherita Morpurgo 2,* 1 Department of Industrial Engineering, University of Padova, via Marzolo, 9, 35131 Padova, Italy; E-Mails: monica.dettin@unipd.it (M.D.); roberta.danesin@unipd.it (R.D.) 2 Department of Pharmaceutical Chemistry and Pharmacology, University of Padova, via Marzolo, 5, 35131 Padova, Italy; E-Mails: davide.silvestri@studenti.unipd.it (D.S.); elisabetta.casarin.1@unipd.it (E.C.) 3 Inter-University Consortium of Veneto for Nanotechnology (CIVEN), via delle Industrie, 5, 30174 Venezia, Italy; E-Mail: cretaio@ 4 Institute of Food Sciences, CNR, via Roma, 64, 83100 Avellino, Italy; E-Mail: picariello@r.it 5 Physics Department, University of Padova, via Marzolo, 8, 35131 Padova, Italy; E-Mails: agnese.sonato@studenti.unipd.it (A.S.); filippo.romanato@unipd.it (F.R.) * Author to whom correspondence should be addressed; E-Mail: margherita.morpurgo@unipd.it; Tel.: +39-049-827-5330; Fax: +39-049-827-5366. Received: 1 June 2012; in revised form: 30 August 2012 / Accepted: 31 August 2012 / Published: 13 September 2012 Abstract: P