AdCMVBMP7促进兔骨髓基质细胞的成骨分化.pdf

中国组织工程研究与临床康复多事J2卷彳萝乃勇铲2008—06—17出版 定死震基础医掌 TiSSUe June17,2008 JournalofClinicalRehabilitative V01．12,No．Z5 EngineeringResearch AdCMV-BMP．7促进兔骨髓基质细胞的成骨分化术★ 施伟伟’，2，叶晓健1，许国华1，顾韬1，何海龙1，张桦1 Osteoblasticdifferentiationofrabbitbonemarrowstromalcells recombinantadeno、，irus by bone cytomegalovirusmOrphOgeneticprotein-7 ShiWei-wsil二。Ye Hual Xiao-jianl。XuGuo．hual．GuTa分，He Hai—tong’，Zhang Abstract of 1Department and the AIM：Bone protein一7 the reconstructionof wasaimed morphogeneticmMP-7)canimproveregeneration cartilage．Thisstudy u^hop8鲫。“toconfirmtheeffectofhumanBMP．7on rabbitbonemalTOWstromalcellstodifferentiatetoosteoclasts． stimulating METHODS：Thewas intheAffiliated ofcheSecond Medical of HCh。awrtgbzhl．e“second experimentcompleted ChangzhengHospital Military University ChjnesePLAfromOctober2005toMarch and Medical 2006．Materials：Plasmid we碑all Military pAdTrack，CMV。pAdEasy．1pGEM-T—BMP一7 ofChinese University donatedDoctorXu coliTGl．DH5a、BJ5183and eellstrain293werestoredinthis adult by Guo