携带溶瘤病毒细胞载体研究进展.pdf

h ttp: / /www. b io ther. o rg Ch in J Cancer B iother, Jun. 2011, V ol. 18, N o. 3 # 331# DOI: 10. 3872/ j. issn. 1007-385X. 2011. 03. 019 # 综 述# Cell carriers for oncolytic vir ses: recent progress 陈艳, 钱其军 (第二军医大学 东方肝胆外科医院, 上海 200438 [ ] , , / 0 , , : , T ; , ; , , , [ ] ; ; [ ] R 730. 5 [ ] A [] 1007-385X ( 2011 03-0331-06 -( m a- , jor h istocompatib ility comp lex, MH C , , [ 1-3] , , A ST , A ST [ 7-11] , AST : , A ST , , , T [ 11] , , [ 12-13 ] , A ST / 0, AST , [ 14-15] , , A ST , ( 1 , , , T , , 1 A ST , 1. 2 细胞因子诱导的 伤细胞 , , ( cytok ine- induced , k iller ce l,l C IK T , IFN-BIL-2 CD 3 CD3+ CD56+ T , NK T [ 16-17 ] C IK 1. 1 抗原特异性 T 细胞 MHC , , T ( antigen-specific T ce l,l A ST + + [] ( 863 ( N o. CD4 CD8 , 2007AA 02 10 10 Project supported by the K ey Foundat ion of N at ion al , H igh T echnology R esearch and D evelopm ent Program (