sub-optimal cd4 reconstitution despite viral suppression in an urban cohort on antiretroviral therapy (art) in sub-saharan africa frequency and clinical significance次优cd4调整尽管病毒抑制城市群体在抗逆转录病毒治疗(art)在撒哈拉以南非洲地区频率和临床意义.pdf

AIDS Research and Therapy BioMed Central Research Open Access Sub-optimal CD4 reconstitution despite viral suppression in an urban cohort on Antiretroviral Therapy (ART) in sub-Saharan Africa: Frequency and clinical significance 1 1 2 Damalie Nakanjako* , Agnes Kiragga , Fowzia Ibrahim , 1 1 1,2 Barbara Castelnuovo , Moses R Kamya and Philippa J Easterbrook Address: 1Infectious Diseases Institute, Facluty of Medicine, Makerere University Kampala, Uganda and 2Department of HIV/GUM, Kings College London, SWZ, London, UK Email: Damalie Nakanjako* - drdamalie@; Agnes Kiragga - akiragga@idi.co.ug; Fowzia Ibrahim - fowzia.ibrahim@kcl.ac.uk; Barbara Castelnuovo - bcastelnuovo@idi.co.ug; Moses R Kamya - mkamya@infocom.co.ug; Philippa J Easterbrook - peasterbrook@idi.co.ug * Corresponding author Published: 28 October 2008 Received: 22 July 2008 Accepted: 28 October 2008 AIDS Research and Therapy 2008, 5:23 doi:10.1186/1742-6405-5-23 This article is available from: /content/5/1/23 © 2008 Nakanjako et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background: A proportion of individuals who start antiretroviral therapy (ART) fail to achieve