syntheses of (diacetoxyiodo)arenes or iodylarenes from iodoarenes, with sodium periodate as the oxidant(diacetoxyiodo)芳烃的合成或从iodoarenes iodylarenes,以高碘酸钠为氧化剂.pdf

Molecules 2001, 6, 881-891 molecules ISSN 1420-3049 Syntheses of (Diacetoxyiodo)arenes or Iodylarenes from Iodoarenes, with Sodium Periodate as the Oxidant† Pawel Kazmierczak, Lech Skulski* and Lukasz Kraszkiewicz Chair and Laboratory of Organic Chemistry, Faculty of Pharmacy, Medical University, Banacha 1, PL 02-097 Warsaw, Poland † This paper was presented at the Fifth Electronic Conference on Synthetic Organic Chemistry (ECSOC-5), September 1-30, 2001 (Paper A0005). * Author to whom correspondence should be addressed; Tel/Fax: +48(22)8226843; e-mail: lskulski@.pl Received: 27 September 2001; in revised form 11 October 2001 / Accepted: 12 October 2001 / Published: 31October 2001 Abstract. - Easy, safe, and effective novel methods for preparing either (diacetoxyiodo)- arenes, ArI(OAc) , or iodylarenes, ArIO , from the corresponding iodoarenes, ArI, using 2 2 sodium periodate as the oxidant are presented in this paper. In order to obtain 2- and 4- iodylbenzoic acids, the respective sodium salts of 2- and 4-iodobenzoic acids should be used as the starting substrates, because mixtures containing the corresponding iodosyl derivatives as the main products along with the intended iodyl compounds are produced from the free parent acids. Keywords: (Diacetoxyiodo)arenes, iodylarenes, iodoarenes, sodium periodate as oxidant Molecules 2001, 6 882 Introduction (Diacetoxyiodo)arenes,