主要组织相容性复合体_MHC_研究进展_马丽颖.pdf

2005 6 June, 2005 15 3 CHINESE JOURNAL OF COMPARAT IVE MEDICINE Vol . 15 No . 3 MHC) 马丽颖, 岳秉飞 , 100050) MHC) , , MHC MHC, MHC T NK , MHC ; ; Q352 A 2005) Advances in Research on Major Histocompatibility Complex MA Li ying, YUE Bingfei National Institute for the Control of Pharmaceutical and Biological Products, Beijing 100050, China) Abstract The major histocompatibility complex MHC) associates not only with the transplantation rejection reactions, but also w ith immunological responses in a variety of pathological processes. In this review w e presented recent advances in research on the eff ects of MHC and MHC molecules in transplantation interactions w ith NK cells and T cell) , antigenic peptides, gene transf er induced immunological resistance and gene therapy, etc. Key words Major histocompatibility complex MHC) ; Tranplantation ; Immunology; Genes 1936 TAP) , MHC) MHC , MHC , , H2 , CD8+ T T CR HLA , HLA MHC MHC , , MHC MHC , HPLC) , , 1 MHC [ 1] 11 MHC GFP) HC MHC [ 2] HFRSV NP