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Sensors 2012, 12, 13002-13018; doi:10.3390/s121013002 OPEN ACCESS sensors ISSN 1424-8220 /journal/sensors Article The Detection of Patients at Risk of Gastrointestinal Toxicity during Pelvic Radiotherapy by Electronic Nose and FAIMS: A Pilot Study James A. Covington 1,*, Linda Wedlake 2, Jervoise Andreyev 2, Nathalie Ouaret 1, Matthew G. Thomas 1,3, Chuka U. Nwokolo 4, Karna D. Bardhan 5,6 and Ramesh P. Arasaradnam 4,6 1 School of Engineering, University of Warwick, Coventry CV4 7AL, UK; E-Mails: N.Ouaret@warwick.ac.uk (N.O.); M.G.Thomas@warwick.ac.uk (M.G.T.) 2 Department of Nutrition and Dietetics and the GI Unit, The Royal Marsden NHS Foundation Trust, Fulham Road, London SW3 6JJ, UK; E-Mails: box46@ (L.W.); J@andreyev.demon.co.uk (J.A.); R.Arasaradnam@warwick.ac.uk (R.P.A.) 3 MOAC Doctoral Training Centre, University of Warwick, Coventry CV4 7AL, UK 4 University Hospital Coventry Warwickshire, Coventry CV2 2DX, UK; E- i hu w uh w hs u 5 Department of Gastroenterology, Rotherham General Hospital, Rotherham S60 2UD, UK; E-Mail: bardhan.sec@rothgen.nhs.uk 6 Clinical Sciences Research Institute, University of Warwick, Coventry CV2 2DX, UK * Author to whom correspondence should be addressed; E-Mail: J.A.Covington@warwick.ac.uk; Tel.: +44-24-7657-4494; Fax: +44-24-7641-8922. Received: 21 July 2012; in revised form: 10 September 2012 / Accepted: 10 September 2012 / Published: 26 September 2012 Abstract: It is well known that the electronic nose can be used to identify differences between human health and di