study on the expression and clinical significances of lewis y antigen and integrin αv, β3 in epithelial ovarian tumors研究刘易斯y抗原的表达及临床意义和整合素αv,β3在卵巢上皮肿瘤.pdf

Int. J. Mol. Sci. 2011, 12, 3409-3421; doi:10.3390/ijm OPEN ACCESS International Journal of Molecular Sciences ISSN 1422-0067 /journal/ijms Article Study on the Expression and Clinical Significances of Lewis y Antigen and Integrin αv, β3 in Epithelial Ovarian Tumors Yifei Wang 1,2, Juanjuan Liu 1, Bei Lin 1,*, Changzhi Wang 2, Quanrong Li 1, Shuice Liu 1, 1 1 3 Limei Yan , Shulan Zhang and Masao Iwamori 1 Department of Obstetrics and Gynecology, Shengjing Hospital Affiliated to China Medical University, Shenyang 110004, China; E-Mails: converting@163.com (Y.W.); juanjuanliu_lg@ (J.L.); dwli_ll@163.com (Q.L.); liushuicc@ (S.L.); limeimei@126.com (L.Y.); zhangshl99@126.com (S.Z.) 2 Department of Obstetrics and Gynecology, the Second Affiliated Hospital of Dalian Medical University, Dalian 116027, China; E-Mail: changzhiw@163.com 3 Department of Biochemistry, Faculty of Science and Technology, Kinki University, 3-4-1 Kowakae, Higashiosaka, Osaka 577-8502, Japan; E-Mail: iwamori@163.com * Author to whom correspondence should be addressed; E-Mail: linbei88@; Tel.: +86-24-96615-1-41511. Received: 27 April 2011; in revised form: 17 May 2011 / Accepted: 18 May 2011 / Published: 27 May 2011 Abstract: Objective: To detect the expression and clinical significances of Lewis y antigen and integrin αv, β3 in epithelial ovarian tumors, and to explore the expression correlation between Lewis y