【精品PPT】天津市科技发展计划项目申请书(科技攻关重点项目).ppt

* * * * * * * * * * * * * * * * * * * SELDI 主要有两类芯片化学表面芯片和生物表面芯片。主要 Description of different SELDI surfaces available. Please refer to new price list for complete overview. * Three dimensions of separation are used for profiling complex biological mixtures such as cell lysate or biofluids. The first dimension is surface-type (eg. Reverse phase, ion exchange etc.), the second is wash stringency (pH, salt, detergent modulation etc.) and the final dimension is the mass readout in Daltons. For each surface and wash condition you get a different protein fingerprint that can be used to look for differential protein analysis of control and test samples. Just 3 surfaces and 6 wash conditions can reveal between 500 and 1000 different proteins. * * * * （一）Cytokines IL-1α IL-1? IL-1ra IL-2 IL-2Rα IL-3 IL-4 IL-5 IL-6 IL-7 IL-8 IL-9 IL-10 IL-12(p40) IL-12(p70) IL-13 IL-15 IL-16 IL-17 IL-18 Basic FGF G-CSF GM-CSF GRO- α HGF ICAM-1 IFN- α2 IFN-γ IP-10 LIF MCP-1(MCAF) MCP-3 M-CSF MIF MIG MIP-1α MIP-1β β–NGF PDGF-BB CTACK Eotaxin RANTES SCF SCGF- β SDF-1α TNF- α TNF- β TRAIL VCAM-1 VEGF Human(50） 小鼠（32） IL-1α Basic FCF TNF-α IL-1β Eotaxin VEGF IL-2 G-CSF IL-3 GM-CSF IL-4 IFN- γ IL-5 KC IL-6 LIF IL-9 MCP-1(MCAF) IL-10 M-CSF IL-12(p40) MIG IL-12(p70) MIP-1α IL-13 MIP-1β IL-15 MIP-2 IL-17 PDGF-BB IL-18 RANTES 大鼠（9） IL-1α IL-1β IL-2 IL-4 IL-6 IL-10 GM-CSF IFN-γ TNF-α （二）Biomarker 多肿瘤标志物联合检测 艾芯TM（肿瘤全套9项） AFPCEA双检液芯（常规体检2项） 肺芯TM（肺癌4项） 消芯TM（消化肿瘤5项） 妇芯TM（妇科肿瘤5项） PSA双检液芯（前列腺癌2项） （三）磷酸化蛋白和总