奥曲肽持续泵入治疗重症胰腺炎38例.pdf

• I自床医药­ 2013 年 12 月 5 日第22 卷第23 期 1 1到 23 壮 Clinical Medicine China Pharmaceuticals Vol. 22 , No. 23 , December 5, 2013 奥曲肤持续-入蚀重症膜腺山 a 例 来 ，目拧 iE顾腺爽 3 惆 杨琼英 (四川省达州市第二人民医院消化内科，四川达州 635000) 摘要:目的探讨奥曲肤持续泵入治疗重症且是腺炎的临床疗效。方法将收治的重症且是腺炎患者 76 例按随机数字表法随机分为研究组 和对照组，其中对照纽仅采用常规禁食、胃肠减压，给予浮托拉哇、丹参、低分子右旋糖肝，研究组在此基础上采用奥曲肤持续泵入治 疗。比较两组患者的临床疗效、症状体征消失时间及不良反应发生率。结果研究纽的显效率和总有效率均明显高于对照纽(矿 =5.28 ， 4. 55 , P O. 05) ;腹痛腹胀消失时间、血淀粉酶恢复时间、尿淀粉酶恢复时间、股腺水肿改善时间、白细胞恢复时间均较对照纽明显缩 短(t =3. 62 , 4. 96 , 3. 05 , 3.11 , 3.67 , PO. 05); 不良反应发生率明显低于对照纽(矿=3. 95 , P O. 05) 。结论奥曲肤持续泵入治疗重 症膜腺炎具有良好的临床疗效，不良反应发生率低，值得临床推广。 关键词:奥曲肤;持续;泵入;重症族腺炎 中图分类号:R969. 4; R975 文献标识码:A 文章编号:1006 -493 1(2013)23 -0066 -02 Clinical Efficacy Octreotide Continuous Pumping in Treating Severe Acute Pancreatitis in 38 Cases Ya吨 Q白吨ying (Department of Gastroenterology, Dazhou Municipal Second People s 日出pital， D皿hou， Sichuan, China 635000) Abstract: Objective To investigate the clinical effect of octreotide continuous pumping in treating severe acute pancreatitis. Methods Seventy - six patients with severe acute pancreatitis were randomly divided into the study group and the control group according to the random number table. The control group was only treated with routine fasting , gastrointestinal decompression , pantoprazole , radix salviae miltiorrhizae and low molecular dextran , while the study group was treated with octreotide continuous pumping based on the above treat- ment. The clinical efficacy, symptoms and signs disappearance time and th