血液透析患者肾性贫血的静脉补铁临床应用分析.pdf

CHINESECOMMUNITYDOCTORS论著·临床论坛

血液透析患者肾性贫血的静脉补铁临床应用分析

张晓红

063000河北省唐山市长生血液透析中心血透室，河北唐山

doi:10.3969/j.issn.1007-614x.2020.07.023

摘要目的：探讨血液透析患者肾性贫血的静脉补铁临床应用效果。方法：2016年9月-2018年12月收治肾性贫血

患者42例，按治疗方式不同分为两组，各21例。对照组实施右旋糖酐铁注射液治疗，试验组实施蔗糖铁注射液治

疗。比较两组血清铁蛋白、血清铁浓度、转铁蛋白饱和度及总铁结合力。结果：试验组血清铁蛋白、血清铁浓度、转

铁蛋白饱和度、总铁结合力均优于对照组。结论：对血液透析患者肾性贫血予以蔗糖铁注射液治疗能有效改善患者肾

性贫血状况，提高治疗效果。

关键词血液透析；肾性贫血；蔗糖铁注射液；右旋糖酐铁注射液

Clinicalapplicationofintravenousironsupplementationinhemodialysispatientswithrenalanemia

ZhangXiaohong

HemodialysisRoom,ChangshengHemodialysisCenterofTangshanCity,HebeiProvince,HebeiTangshan063000

AbstractObjective:Toexploretheclinicalapplicationeffectofintravenousironsupplementationinhemodialysispatientswith

renalanemia.Methods:FromSeptember2016toDecember2018,42patientswithrenalanemiawereselected.Accordingto

differenttreatmentmethods,theyweredividedintotwogroupsof21casesineach.Thecontrolgroupwastreatedwithdextraniron

injection;theexperimentalgroupwastreatedwithsucroseironinjection.Wecomparedtheserumferritin,serumironconcentration,

transferrinsaturationandtotalironbindingcapacitybetweenthetwogroups.Results:Intheexperimentalgroup,serumferritin,

serumironconcentration,transferrinsaturationandtotalironbindingcapacitywerebetterthanthoseinthecontrolgroup.the

differencewasstatisticallysignificant(P＜0.05).Conclusion:Thetreatmentofhemodialysispatientswithrenalanemiawithsucrose

ironinjectioncaneffectivelyimprovethestatusofrenalanemiaandimprovethetherapeuticeffect.

KeywordsHemodialysis;Renalanemia;Sucroseironinjection;Dextranironinjection

肾性贫血是患者进行血液透析治疗排除标准：①铁剂过敏；②恶性肿异常反应后，再将剩余剂量滴注完毕，对

所产生的严重并发症，与患者肾功能衰瘤；③肝、肾功能严重器质性损害；④于功能性铁缺乏或维持性铁剂治疗患者，

竭后期肾脏分泌促红细胞生成素减少有无自主意识；⑤不愿参与此次研究。