GPER1激动剂及拮抗剂2016.pdf

Accepted Manuscript Title: Understanding the Molecular Basis of agonist/antagonist mechanism of GPER1/GPR30 through structural and energetic analyses ´ ´ Author: David Mendez Luna Martiniano Bello Jose Correa-Basurto PII: S0960-0760(16)30001-2 DOI: /doi:10.1016/j.jsbmb.2016.01.001 Reference: SBMB 4608 To appear in: Journal of Steroid Biochemistry Molecular Biology Received date: 2-11-2015 Revised date: 13-12-2015 Accepted date: 4-1-2016 ´ ´ Please cite this article as: David Mendez Luna, Martiniano Bello, Jose Correa-Basurto, Understanding the Molecular Basis of agonist/antagonist mechanism of GPER1/GPR30 through structural and energetic analyses, Journal of Steroid Biochemistry and Molecular Biology /10.1016/j.jsbmb.2016.01.001 This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain. Understanding the Molecular Basis of agonist/antagonist mechanism of GPER1/GPR30 through structural and energetic analyses * David Méndez Luna, Martiniano Bello bellomartini@ mbellor@ipn.mx, José Correa-Basurto Laboratorio de Modelado Molecular, Bioinformática y Diseño de Fármacos de la Escuela Superior de Medicina, Instituto Politécnico Nacional, México. Plan de San Luis Y Diaz Mirón S/N, Col. Casco de Santo Tomas, Mexico City, México. CP: 11340.