纤维支气管镜肺泡灌洗治疗小儿重症肺炎的临床效果观察.docx

纤维支气管镜肺泡灌洗治疗小儿重症肺炎的临床效果观察\o分享到微博\o分享到微信\o分享到QQ\o分享到QQ空间

【摘要】目的：探讨纤维支气管镜肺泡灌洗治疗小儿重症肺炎的价值。方法：选取80例重症肺炎患儿进行实验，随机将其分为两组，每组40例，一组为对照组，接受常规的治疗；另一组为观察组，在常规治疗的基础上增加应用纤维支气管镜肺泡灌洗治疗。比较两组患儿临床疗效、炎症因子（CRP、IL-6及TNF-α）水平及症状缓解时间。结果：观察组治疗总有效率明显高于对照组，差异具有统计学意义（P0.05）；治疗7d后，观察组患儿血清CRP、IL-6及TNF-α水平低于对照组，差异具有统计学意义（P0.05）；观察组的各症状缓解时间短于对照组，差异具有统计学意义（P0.05）。结论：针对小儿重症肺炎，采取纤维支气管镜肺泡灌洗治疗具有良好效果，可缓解患儿炎症，促进患儿症状早期改善，值得推广。

【关键词】小儿重症肺炎；纤维支气管镜肺泡灌洗；疗效；炎性因子

Observationoftheclinicaleffectoffiberopticbronchoscopealveolarlavageinthetreatmentofseverepneumoniainchildren

JIANGChang’an，LUZhonghua，YINDachi

DepartmentofPediatrics，JiangsuShuyangMingheHospital，Suqian，Jiangsu223600，China

【Abstract】Objective：Toexplorethevalueoffiberopticbronchoscopealveolarlavageinthetreatmentofseverepneumoniainchildren.Methods：80childrenwithseverepneumoniawereselectedfortheexperiment，andtheywererandomlydividedintotwogroups，with40casesineachgroup.Onegroupservedasthecontrolgroupandreceivedconventionaltreatment；Theothergroupservedastheobservationgroupandreceivedadditionalfiberopticbronchoscopealveolarlavagetherapyonthebasisofconventionaltreatment.Theclinicalefficacy，levelsofinflammatoryfactors（CRP，IL-6andTNF-α）andsymptomsrelieftimebetweenthetwogroupsofchildren.Results：Thetotaleffectiverateoftreatmentintheobservationgroupwassignificantlyhigherthanthatinthecontrolgroup，andthedifferencewasstatisticallysignificant（P0.05）；After7daysoftreatment，thelevelsofserumCRP，IL-6andTNF-αintheobservationgroupwerelowerthanthoseinthecontrolgroup，withsignificantdifference（P0.05）；Thetimeforsymptomsreliefintheobservationgroupwasshorterthanthatinthecontrolgroup，withsignificantdifference（P0.05）.Conclusion：Forseverepneumoniainchildren，fiberopticbronchoscopealveolarlavagetreatmenthasgoodefficacy，canalleviateinflammationinchildren，promoteearlyrelie