阴道微生态与人乳头瘤病毒感染和宫颈病变的相关性研究 .pdf

阴蹒常与人乳口宫的相关ffii开究

【摘要】目的：探讨阴道微生态同人乳头瘤病毒(HPV)感染和宫颈病变的相关性方法：选择2023年1月-2024

年4月宫颈癌筛查的女性80例作为研究对象，均进行阴道微生态、HPV以及宫颈病原体检测，分析检测结果以及结果

间的相关性结果：80例接受检查者，细菌性阴道炎的阳性检出率最高(72.50%),HPV阳性率为46.25%,宫颈病

变阳性率为30.00%HPV感染的乳酸杆菌异常率、细菌性阴道炎阳性率及霉菌性阴道炎阳性率均高于非HPV感染

(Pv0.05)宫颈病变的pH值4.5率、乳酸杆菌异常率、细菌性阴道炎阳性率、霉菌性阴道炎阳性率及滴虫性阴道炎

阳性率均高于非宫颈病变(Pv0.05)多因素分析证实pH值4.5、乳酸杆菌异常、细菌性阴道炎、霉菌性阴道炎及滴

虫性阴道炎均是宫颈病变发生的独立危险因素结论：女性阴道微生态失衡同HPV感染以及宫颈病变存在显著相关性，

通过纠正阴道微生态失衡可预防宫颈病变发生

【关键词】阴道微生态；人乳头瘤病毒；宫颈病变

Correlationovaginalmicrobiotawithhumanpapillomavirusinectionandcervicallesions

HUXiaoyan,WANGShengqing

TheFirstPeoplesHospitaloBaiyinCity,Baiyin,Gansu730900,China

［Abstract］Objective：Toinvestigatethecorrelationbetweenvaginalmicrobiotaandhumanpapillomavirus

(HPV)inectionandcervicallesions.Methods：Atotalo80womenwhowerescreenedorcervicalcancerrom

January2023toApril2024wereselectedasthestudysubjects,andallothemweretestedorvaginalmicroecology,

HPVandcervicalpathogens,andthecorrelationbetweenthetestresultsandresultswasanalyzed.Results：Among

the80examiners,thepositivedetectionrateobacterialvaginosiswasthehighest(72.50%),thepositiverateo

HPVwas46.25%,andthepositiverateocervicallesionswas30.00%.Theabnormalrateolactobacillus,positive

rateobacterialvaginosisandpositiverateoungalvaginitisinHPVinectionwerehigherthanthoseinnon-HPV

inection(P0.05).TherateopH4.5,abnormalrateolactobacillus,positiverateobacterialvaginitis,positive

rateoungalvaginitisandpositiverateotrichomonasvaginitisincervicallesionswerehigherthanthosein

non-cervicallesions(P0.05).MultivariateanalysisconirmedthatpH4.5,abnormallactobacillus,bacterialvaginitis,

ungalvaginitis,andtrichomoniasisvaginitiswereindependentriskactorsorcervicallesions.Conc