骨转移性乳腺癌.ppt

Metastatic Breast cancer Case Report General information Name: WU ChunHong Age: 40y Sex: Female Date of admission: February 9th,2011 Date of discharge: April 23th,2011 Chief complaint She got hypoesthesia of lower limbs and inability to walk for more than a month History of present illness The patient felt pain on the back by no obvious incentives in June 2010 The pain was tingling, especially in night-time The patient took orally traditional Chinese medicine , but had not tangible effects Past, Personal Family History No hepatitis, hypertension, or diabetes No smoking, alcohol or drug abuse No inherited diseases No history of drug allergy Normal menstruation Clinical findings The left breast presented with diffused erythema and edema , induration about size of 3.0cm*3.0cm Ultrasound examination a 3 cm left breast mass and a normal right breast Thoracic MRI examination  Thoracic MRI examination High-density mass was shown on the seventh thoracic, and bone destruction also had been found. Enhanced MRI Laboratory examination 2011-02-09 1.Hepatic functions ALT 40 U/L AST 20 U/L TB Normal 3.Tumor markers CA19-9 Normal 2. Blood routine test Hb 82 g/L  RBC 4.54×1012 /L WBC 6.1×109 /L PLT 201 ×109 / L puncture biopsy She received ultrasound guided breast core needle puncture biopsy Puncture tissue pathology :The left breast invasive ductal carcinoma Primary diagnosis Breast cancer with bone metastasis Treatment On February 11, 2011 in orthopedic department, The Patient received the seventh thoracic tumor resection and pedicle screw fixation Histological examination Seventh thoracic tumors was identified as metastatic carcinoma, and the immunohistochemistry results showed the possibility of breast cancer bone metastasis was very large IMMUNOHISTOCHEMICAL results ER++ PR++ CerbB2- CK20- EMA++,Ckpan+++,CK5/6- Treatment The patient recovered well , and then transfer