18F-FDG PET_CT对老年结肠癌的诊断价值.docx

18F-FDGPET/CT对老年结肠癌的诊断价值

朱标王宗火江慎林洪琪

[中图分类号]?R445；R735.3??????[文献标识码]?A??????[DOI]?10.3969/j.issn.1673-9701.2024.04.013

Diagnostic?value?of?18F-FDG?PET/CT?in?elderly?patients?with?colon?cancer

ZHU?Biao，?WANG?Zonghuo，?JIANG?Shenlin，?HONG?Qi

CT?Room，?Jingdezhen?Hospital?of?Traditional?Chinese?Medicine，?Jingdezhen?333000，?Jiangxi，?China

[Abstract]?Objective?To?analyze?diagnostic?value?of?18F-fluorode-oxyglucose?（18F-FDG）?positron?emission?tomography?and?computed?tomography?（PET/CT）?in?elderly?patients?with?colon?cancer.?Methods?A?total?of?102?patients?with?colon?cancer?admitted?to?Jingdezhen?Hospital?of?Traditional?Chinese?Medicine?from?January?2021?to?December?2022?were?retrospectively?selected?to?analyze?the?relationship?between?18F-FDG?PET/CT?imaging?and?clinical?features?and?its?diagnostic?value.?Results?The?typical?18F-FDG?PET/CT?imaging?of?colon?cancer?was?mainly?concentrated?in?ascending?colon，?transverse?colon，?descending?colon，?and?sigmoid?colon.?The?glucose?metabolism?of?each?part?increased，?the?intestinal?wall?thickened，?and?standardized?uptake?value?（SUV）?increased.?There?were?statistically?significant?differences?in?SUV?among?colon?cancer?patients?with?different?vertical?thickness?of?the?lesion，?gender?and?lymph?node?metastasis?（P0.05）.?SUV?was?positively?correlated?with?vertical?thickness?of?the?lesion?and?lymph?node?metastasis?（P0.05）.?Receiver?operating?characteristic?curve?results?showed?that?the?area?under?the?curve?of?18F-FDG?PET/CT?for?diagnosis?of?colon?cancer?lymph?node?metastasis?was?0.993，?the?sensitivity?was?97.2%，?and?the?specificity?was?100%.?Conclusion?18F-FDG?PET/CT?for?the?diagnosis?of?elderly?patients?with?colon?cancer?has?a?high?clinical?application?value.

[Key?words]?18F-FDG?PET/CT;?Elderly;?Colon?cancer;?Metastasis

1??资料与方法

1.1??一般资料

1.2??方法

患者注射18F-FDG前禁食6h以上，监测血糖。按3.70～5.55MBq/kg标准注射放射性核素18F-FDG（批准文号：国药准字生产单位：江苏华益科技有限公司，规格：0.37～7.40GBq），注射完成后患者静卧休息1h，而后进行PET/CT扫描（西门子，Biograph?Vision）。扫描前排空膀胱，饮水200～500ml，先进行传统CT扫描，而后进行