12 edwards pascal transcatheter valve repair system12爱德华兹导管维修系统.pdf

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TheEdwardsPASCALTranscatheterValveRepairSystem

MirjamWinkel,StephanWindecker,andFabienPraz

DepartmentofCardiology,Inselspital,UniversityofBern,Bern,Switzerland

12.1Introduction12.2TheEdwardsPASCAL™

TranscatheterValveRepairSystem

Techniquesfortranscathetermitralvalve

repairarederivedfromsurgicalproceduresToaddresssomeoftheselimitations,the

suchastheAlfieriedge-to-edgerepairaim-EdwardsPASCALtranscathetervalverepair

ingforleafletapproximation

[1].Thesystem(EdwardsLifesciences,Irvine,CA,

MitraClip(Abbott,AbbottPark,IL,USA)wasUSA)hasbeendevelopedandhasobtained

thefirstwidelyavailabletranscathetersystemCEmarkapprovalforthetreatmentofthe

withapprovalforthetreatmentofbothpri-mitralvalvein2019andforthetricuspid

maryandsecondarymitralregurgitationvalvein2020.

(MR).Itsminimallyinvasiveapproachena-ThePASCALrepairsystemconsistsof

blesfasterpatientrecoveryandprovidesathreetcatheters:a22French

highsafetyprofilewithalowerrateofperipro-steerableguidesheath,asteerablecatheter,

ceduralcomplications.However,sinceitsfirstandanimplantcatheterwiththeimplant

implantationin2003

[2,3],anddespitemorepreattachedtoitsdistalend.Theguide

than100000proceduresperformedworld-sheathandsteerablecatheterareflexed

wide,therehavebeenonlyminimald