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·112 · 国外医学卫生学分册  2009 年  第 36 卷  第 2 期 [ 12 ]  TURLE J , RUSCETTI F , KIM S J , et al . Vitamin E [ 18 ]  PRASAD K N , PRASAD E J . Vitamin E and cancer succinate inhibits proliferation of BT20 human breast cancer prevention : Recent advances and future potentials[J ] .J Am cells : increased binding of cyclic amp negatively regulates Coll Nutr ,1992 ,11 :487500 . E2F transactivation activity [ J ] . Cancer Res , 1997 , 57 : [ 19 ]  BLUMENTHAL R D , LEW W , REISIN G A , et al . Anti oxidant vitamins reduce normal tissue toxicity induced by [ 13 ]  ISRAEL K , YU W , SANDERS B G , et al . Vitamin E radioimmune therapy [J ] . Int J Cancer , 2000 , 86 :27680 . succinate induces apoptosis in human prostate cancer cells : [20 ]  JAAKKOLA K , LAHTEENMAKI P , LAAKSO J , et al . role for fas in vitamin E succinatetriggered apoptosis [J ] . Treatment with antioxidant and other nutrients in Nutr Cancer ,2000 ,36 : 90100 . combination with chemotherapy and irradiation in patients [ 14 ]  SCHWARTZ J L . Molecular and biochemical control of with smallcell lung cancer [J ] . Alticancer Res , 1992 , 12 : tumor growth following treatment with carotenoids or 599606 . tocopherols[J ] . Nutr Cancer Prev Treat ,1995 ,8 :287316 . [21]  LAMSON D V T , BRIGNALL M S. Antioxidants in cancer [ 15 ]  ZHAN GL X , COONEY R V , BERTRAM J S. Carotenoids therapy ; their actions and interactions with oncologic upregulate connexin43 gene expression independent of therapies[J ] . Atern Med Bev ,1999 ,4 :304329 their provitamin A or antioxidant proper
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