壳聚糖快速止血材料的研究进展.pdf

ISSN 1002-4956 　　　　　　 26　3 　2009 3 CN11-2034/T 　　　　　　　　 　　　Experimental Technology andManagement　　　　　　 Vol.26　No.3　Mar.2009 李保强, 韦其全,刘　坤,潘　峰, 方一帆 (哈尔滨工业大学 特种陶瓷研究所, 黑龙江 哈尔滨　150001) 　:, 。 。、 。, , , 。 :;;; :R973;O636　　:A　　:1002-4956(2009)03-0034-03 Research progress of chitosaninrapid hemostaticmaterials Li Baoqiang, ei Qiquan, Liu Kun, Pan Feng, Fang Yifan (Institute for Advanced Ceramics, Harbin Institute of Technology, Harbin 150001, China) Abstract:Uncontrolledhemorrhage is the leading causeof unpreventableaccidents, massive hemorrhageduring surgery and battlefield casualty.Effective control of hemorrhage can reduce the deaths and save lives signifi- cantly.Hemostasis material consisting of chitosan or their derivative involves many excellences such as non- toxicity, antibacterial action, biodegradability and the stimulation inwoundhealing.Thepurposeof this article is to summarize the research progressin the chitosan hemostaticmaterials, hemostaticevaluation, and mecha- nism of hemostasis.Finally, the development of chitosan hemostatic materials in the future will tend to func- tionalize hemostatic materials, such asacceleration of woundedhealing, synergichemostasisunder help of drug or thrombin. Key words:chitosan;hemostatic material;hemostatic mechanism;rapidhemostasis 　　、 。, ,, [5] 。 。 。 。 ,, (、)、(、 ,。 )、, 1 　、 :, , [1] ;, 1.1 　Celox