Grape seed extract 简单培训-Xuxiao概要1.pptx

Grape seed extract;;Grape Seed Extract (GSE) is a supplement derived from grape seeds which is a vessel for proanthocyanidin/procyanidin molecules (the two terms are used interchangeably). Procyanidins are found in a wide variety of foods, and the main human dietary sources appear to be fruits (apples, grapes, berries, plums), beverages (tea, cocoa,?Wine), cereals grains (sorghum, barley), nuts, and chocolate via the?Cocoa Extract and the estimated daily intake is approximately 53.7mg. Different sources of procyanidins may have different effects on the body, depending on how the catechin chains are formed and bound to each other.;Mian ingredients of Grape Seed Extract(GSE);PPC: pentamer and above OPC: dimer, trimer, tetramer Mainly Monomers: gallic acid, epigallocatechin gallate(EGCG), Catechin, epicatechin (Accounted for?more than 90%);Gallic acid?is a?trihydroxybenzoic acid, a type of phenolic acid, a type of organic acid, also known as 3,4,5-trihydroxybenzoic acid, found in?gallnuts,?sumac,?witch hazel,?tea?leaves,?oak bark, and otherplants.;Epigallocatechin gallate?(EGCG), also known as?epigallocatechin-3-gallate, is the?ester?ofepigallocatechin?and?gallic acid, and is a type of?catechin. EGCG, the most abundant catechin in?tea, is a?polyphenol?under?basic research?for its potential to affect human health and disease. ;Catechin?/?k?t?t??n/?is a?flavan-3-ol, a type of natural phenol and?antioxidant. It is a?plant?secondary metabolite. It belongs to the group of?flavan-3-ols?(or simply flavanols), part of the chemical family of flavonoids.;Catechin possesses two benzene rings (called the A- and B-rings) and a dihydropyran?heterocycle (the C-ring) with a hydroxyl group on carbon 3. The A ring is similar to a?resorcinol?moiety while the B ring is similar to a?catechol?moiety. There are two?chiral?centers on the molecule on carbons 2 and 3. Therefore, it has four diastereoisomers. Two of the isomers are in?trans configuration?and are called?catechin?and the other