skeletal muscle oxygen saturation does not estimate mixed venous oxygen saturation in patients with severe left heart failure and additional severe sepsis or septic shock骨骼肌氧饱和度不估计混合静脉严重左心衰竭患者的血氧饱和度和额外的严重脓毒症或脓毒性休克.pdf
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Vol 11 No 1 Open Access
Research
Skeletal muscle oxygen saturation does not estimate mixed
venous oxygen saturation in patients with severe left heart failure
and additional severe sepsis or septic shock
Matej Podbregar and Hugon Možina
Clinical Department for Intensive Care Medicine, University Clinical Centre, Zaloska 7, 1000 Ljubljana, Slovenia
Corresponding author: Matej Podbregar, Matej.Podbregar@guest.arnes.si
Received: 13 Oct 2006 Revisions requested: 22 Nov 2006 Revisions received: 30 Nov 2006 Accepted: 16 Jan 2007 Published: 16 Jan 2007
Critical Care 2007, 11:R6 (doi:10.1186/cc5153)
This article is online at: /content/11/1/R6
© 2007 Podbregar and Možina; licensee BioMed Central Ltd.
This is an open access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0),
which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Introduction Low cardiac output states such as left heart failure healthy volunteers (P = 0.02). In group A StO2 correlated with
are characterized by preserved oxygen extraction ratio, which is SvO2 (r = 0.689, P = 0.002), although StO2 overestimated
in contrast to severe sepsis. Near infrared spectroscopy (NIRS) SvO2 (bias -2.3%, precision 4.6%). In group A changes in StO2
allows noninvasive estimation of skeletal muscle tissue correlated with changes in SvO2 (r = 0.836, P 0.001; ΔSvO2
oxygenation (StO2). The aim of the study was to determine the = 0.84 × ΔStO2 - 0.67). In group B important differences
relationship bet
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