《皮肤性病学》psoriasis银屑病(英文)-教学课件（非AI生成）.ppt

PSORIASIS

1

WhatisPsoriasis?Psoriasisisachronic,inflammatorydermatosischaracterizedbywell-demarcatederythematousplaquestoppedbysilveryscales.2

Howdoespsoriasisoccur?inheritanceenvironmentimmunity3

inheritance16%50%4

environmentinfectionendocrine?tensionstressother:drug、smoke、drink5

infectionTypically,astreptococcalsorethroatmayprecipitateguttatepaoriasis6

endocrinepregnancydelivery7

tensiontensionwoundincitement?bloodvessel、motornerve?psoriasisaggravateinduced8

stresstraumasurgery9

otherDrugBeta-blockers,lithiumandantimalarialscanmakepsoriasisworseorprecipitateit.Cigarettesandalcoholseemtomakepsoriasisworse.10

immunityfactorimmunologydisorderT-LymphocytesCytokinesKeratinocytes11

ClinicalManifestationpsoriasisvulgarispsoriasispustulosapsoriasisarthropathicapsoriasiserythrodermic12

psoriasisvulgarisknee、elbow、sacrumwell-definedredplaquesilver-whitescale13

psoriasisvulgaris14

15

psoriasisvulgaris16

psoriasisvulgarisMembranephenomenon17

psoriasisvulgarisAuspitzsign18

psoriasisvulgarisscalpmucosalnailguttate19

scalpBunchinesshair20

Mucosalglansforeskinoralcavity21

NailPsoriasisaffectsthenailin25-50％ofcases.ThimblepittingOnycholysisthickenToenails22

Thimblepitting23

thicken24

Onycholysis25

Toenails26

GuttateAdolescentsoryoungadultsStreptococcalthroatinfectionAcutesymmetricaleruptionof“drop-like”lesionswithlittlescaleintheearlystageUsuallyonthetrunkandlimbs0.3~0.5cm27

28

29

psoriasisvulgarissometimesitch30

CourseAdvanceStillRecession31

AdvanceKoebnerphenomenon.32

33

34

StillNonewrash35

RecessionRashgraduallyreduced36

psoriasisarthropathica37

psoriasisarthropathica38

psoriasisarthropathica39

psoriasispustulosawithdrawalofsteroidsorimmunodepressant,orpotentstimulationdrugGeneralizedandlocalizedforms40

Generalizedpustularacutesheets,small,sterileyellowishpustulesdeveloponanerythematousbackgroundfever